Recent studies by A. Agaimy and co-authors add new data to gastrointestinal stromal tumors findings.

According to a study from Nurnberg, Germany, "Microscopic gastrointestinal stromal tumors (GISTs) (synonyms: sporadic interstitial cell of Cajal hyperplasia, seedling GISTs, minimal GISTs) are common incidental findings in gastroesophageal resections (9% to 35%). To our knowledge, their frequency, clinicopathologic features, and molecular pathogenesis from nongastroesophageal sites have so far not been sufficiently analyzed."

"We studied 19 lesions from distal esophagus (n = 8), gastroesophageal junction (n = 2), sigmoid colon (n = 5), and vermiform appendix, cecum, rectum, and small intestine (1 each). Microscopic GISTs were detected in 0.2%, 0.1%, and 0.01% of …